Cette approche accorde un rôle majeur aux vétérinaires et propriétaires ou gestionnaires d’animaux ainsi qu'aux personnes en contact régulier avec les faunes domestique et sauvage et l’environnement (et en particulier : éleveurs mais aussi pêcheurs, chasseurs, forestiers et gestionnaires d'espaces protégés). Pour l'OIE, sa mise en œuvre passe par « de nouveaux mécanismes amenant tous ces acteurs à s’informer mutuellement et à agir d’une manière concertée, en liaison avec les gestionnaires de la santé publique qui travaillent le plus souvent dans nos pays membres sous l’égide des ministères de la Santé, qu’ils soient fonctionnaires de l’État, personnels de collectivités ou médecins libéraux »3.
Finally, while many testimonial and anecdotal accounts exist of health improvements following a "detox", these are more likely attributable to the placebo effect; where people actually believe that they are doing something good and healthy. Yet, there is a severe lack of quantitative data. Some changes recommended in certain "detox" lifestyles are also found in mainstream medical advice (such as consuming a diet high in fruits and vegetables). These changes can often produce beneficial effects in and of themselves, and it is accordingly difficult to separate these effects from those caused by the more controversial detoxification recommendations.

Skip juice cleanses or liquid diets. A popular cleansing regimen for losing weight involves drinking only juice or another type of liquid for a few days to a week. This is dangerous because you could end up without essential nutrients. These extreme cleanses are also counterproductive because most people just gain back any weight they lost when they go back to eating normal food again. Doctors don't recommend any sort of diet like this, and say following a healthy diet and exercise routine is much better for losing weight.[15]